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The possibility that the fetal membranes may participate in regulating the steroid environment within the gravid uterus has been considered from several points of view. The intimate contact between the chorioamnion and the decidua, which is thought to be the important site of PG generation, suggests that steroids formed within the membranes regulate PG synthesis. The potential for carrying out steroid transformations was first suggested by the studies of Katz et al . PearFiction casa do apostador Studios. These results are consistent with the more rapid transport of estrogen sulfates than of glucuronides from amniotic fluid. About the same time, Warren and French (1965) showed that homogenates of unseparated human fetal membranes actively hydrolyze DHEAS. In an extensive study of whole tissue fragments, Tseng et al. (1972) demonstrated that human amnion and chorion contain estrogen sulfatase and 17 β -dehydrogenase activities, whereas the chorion, but not the amnion, contain low levels of aromatase activity. Imagens de apostas.
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