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Quantitative ER score = 1/20 * (percent of ER-positive cancer cell nuclei + (average nuclear intensity × 100)). Table 1. Parameter R 2 Correlation Magnitude p -Value % of ER-positive cancer cell nuclei 0.741 Strong Stain intensity in the nuclei 0.638 Strong. There are two major beneficial points in the currently proposed approach; the first one giving the possibility to detect cases of stain intensity that were obscured by the background coloration, and the second, to eliminate the overestimation of the score values by pathologists. The comparison and evaluation of semi-quantitative scoring systems (such as the Allred scoring system) are necessary for the standardization of quantitative ER expression assessment. Thus, the suggested deconvolution method can distinguish different variants of ILC, reduce intra-laboratory variations, and exclude subjectivity during ER analysis. Also, the application of the deconvolution method can be useful for the detection of border-line ER (+) cases which reflects directly on hormonal therapy usage. Teimosinha loteria problema online aposta.Sin Baccarat Variedad de ruletas escasa Pocas promociones selección de ruleta normal.
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