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( c ) Patient n.2 missense mutation HSD3B2 c.370 A>G. ( d ) Patient n.2 intronic mutation HSD3B2 c.308-6 G>A. ( e ) Father’s missense mutation HSD3B2 c.370 A>G. ( f ) Mother’s intronic mutation HSD3B2 c.308-6 G>A. Table 3. 5. Discussion. We report the presence of two novel variants on the HSD3B2 gene in the compound heterozygous form that likely caused the 3βHSD2 deficiency with variable expressivity in two siblings, a missense mutation on exon 4 (c.370 A>G) and an intronic mutation on intron 3 (c.308-6 G>A), whose potential pathogenetic effect were evaluated by in-silico analysis and need functional validation.
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Before proceeding with your purchase please make sure you have taken the right measurements as shown in the “Sizes And Measurements” tab below. If in doubt, please contact us. WHAT IS IT FOR? Shoulder joint instability Dysplasia Joint laxity or hyper-mobility Dislocation Inflammation. The brace simultaneously compresses both shoulders Breathable fabric Adjusts for a better fit Can be hand-washed. Size Approx Dog Weight Approx Height of the dog (Withers) XS 5-12kg / 11-26lb 25 to 45cm / 10 to 17.7inches S 10-20kg / 22-44lb 45 to 60cm / 17.7 to 23.6inches M 20-50kg / 44-110lb 60 to 75cm / 23.6 to 29.5inches L 50-80kg / 110-176lb ONLY GIANT/TALL BREEDS (please contact us before ordering) -The distance between the withers and elbow, or elbow to elbow. RECOMMENDATIONS FOR USE. Best Shoulder Braces For Dogs In 2023. The shoulder braces for dogs can treat arthritis, osteoarthritis, and elbow dysplasia.
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