17 17 Penna GO, Pontes MA, Cruz R, Gonçalves Hde S, Penna ML, Bührer-Sékula S. A clinical trial for uniform multidrug therapy for leprosy patients in Brazil: Rationale and design. Mem Inst Oswaldo Cruz. 2012;107:22-7. Skin pigmentation and xerosis were the most frequent adverse-effects associated with MDT. The similarities of AE in the four arms of the study points to the feasibility of a six-month uniform regimen. Who.int [Internet]. World Health Organization (WHO).
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